Lluis Artus

Earth-abundant metal catalyst for amide hydrogenation to methanol

A recording of his talk can be found here.

Earth-abundant metal catalyst for amide hydrogenation to methanol.

Artus, Ll.; Nova, A.; Balcells, D.; Tilset, M.

Centre for Theoretical and Computational Chemistry (CTCC), 

University of Oslo.

Amides are one of the most abundant functional groups find in most natural molecules.[1] Their low reactivity has driven synthetic chemists to put efforts in creating procedures to activate them. While state-of-art catalysts for amide hydrogenation are currently based on ruthenium,[2] developing more active catalysts using less expensive and toxic metals will enhance the prospects for the large scale utilization of these catalytic systems. In this work we have explored the mechanism of an iron based bifunctional catalysts for amide hydrogenation[3] (Figure 1). DFT studies provided a better understanding of the reaction aiming at the synthesis of improved catalysts in the near future.

Figure 1 Proposed paths for methanol formation from amides.

 

[1] Arthur, G. The amide Linkage: Selected Structural Aspects in Chemistry, Biochemistry, and Materials Science. Wiley-Interscience, Hoboken (2000)

[2] Bergens, S.H. et al., Catal. Sci. Technol. 5 (2015) 1181-1186. 

[3] Hazari, N. Bernskoetter, W.H. et al., Organometallics. 36 (2017) 409-416. 

 

E-mail:     lluisas@kjemi.uio.no

www:    http://www.ctcc.no/

 

This is a joint seminar between Oslo and Tromsø in room V205 (Oslo) and ROOM #1.441 (LEVEL 4) Teorifagbygget, House 1 (Tromsø).

The seminars alternate beetween our two Universities and is broadcasted by video to the other place.

Published May 10, 2017 10:32 AM - Last modified May 19, 2017 4:16 PM